Rescuing protein homeostasis
نویسندگان
چکیده
منابع مشابه
Rescuing doctors in distress.
burnout or depression among physicians: financial cuts, relentless night shifts, long hours of work, overwhelming responsibility, dealing with life-threatening conditions, distress over the limitations of medical care, or just working conditions that have worsened in recent decades as a result of increasing time pressure, competition, explosion of knowledge, administrative loads or lack of auto...
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So far this report has discussed the choices available for digital preservation very much in the sense of forward planning—following a set of logical, ordered steps in order to ensure the preservation of digital material. However, this is not always possible. What if one, or more, of these steps has been omitted? Documentation may be missing. Copying, refreshing or routine back-ups may not have...
متن کاملProtein folding, protein homeostasis, and cancer
Proteins fold into their functional 3-dimensional structures from a linear amino acid sequence. In vitro this process is spontaneous; while in vivo it is orchestrated by a specialized set of proteins, called chaperones. Protein folding is an ongoing cellular process, as cellular proteins constantly undergo synthesis and degradation. Here emerging links between this process and cancer are review...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2012
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd3662